The Captain said:
Uh-oh, you just opened a can of worms. Well, here it goes.
I am a very weak person with next to no self-confidence. I don't like being with other people, and I don't like being at parties. So sometime ago (I can't remember exactly when), I invented a new side to myself -- a front I can use so that I am not afraid (at least on the outside). This is what I refer to as my pride. This pride holds me to a certain standard and mandates what is considered weak and strong. Because of my pride, I am able to lead a normal life more or less. If you walked up to me on the street and started talking to me, you would find that I can carry on a conversation and smile at you reassuringly just as well as the next man. But inside, behind that front, I'm actually scared ****less. My goal is to slowly become the image that my pride invokes -- a person who is not afraid of anything or anyone -- a person who doesn't give a damn about what others think of him and can live independently of others.
Unfortunately, the real me is nothing like the image that my pride manifests. As I said before, I am weak. I do care about what others think of me, and I know that I can't survive without help from others. I'm afraid that no one will ever love me, and I'm angry that the jack-off, retard guys around me can get practically any girl they want.
Most people in my situation would probably commit suicide, I imagine. But I can't. My pride is the only thing that is holding me back from giving up. I CANNOT lose this pride. Whever I think about giving up on life, my pride has an automatic life-preservation mechanism that kicks in. Instead of feeling sorry for myself, I am able to use my pride to change my feelings into aggression towards the outside world. I say to myself, "If they don't love me and don't want to be my friends, then they can just die."
Well that's me in a nutshell. I guess you could compare my pride to the speaker in "Sad but true" by Metallica. I've never told anyone else about this before, so you guys are the only ones that know, and I hope it stays that way. The reason why I don't get therapy or drugs is that I would have to reveal myself to someone else. I would have to throw away my pride and show how weak I truly am. In that case, I'm afraid about what would happen. As I said before, this pride has kept me from thinking about giving up or committing suicide, so it serves its purpose.
I am nearly the same way as you, although I dealt with my depression and got rid of it at an early stage of life (I distinctly remember contemplating suicide with a knife to my belly at the age of 8, and a distinctive personality shift at around the age of 12-13, although I inherently remained nearly the same person).
I think what I finally understood is that I had something more to live for. Whatever that something is, I don't know, but I'm more than ready to live for it. If all I ever do is help out those around me to have a better life than if I weren't there, then it will have been worth going on.
Honestly, as long as you stand up for yourself without "talking ****" needlessly, and you do your best to talk to women when the opportunity arises, you'll most likely be just fine. Every guy you've seen who "gets every girl he wants" has been rejected far more times than you have. It's more a matter of determination and being open with others that gets him the women (Although part of it is looks, looks DO NOT have everything to do with it). Also, remember that a woman is a person just like you are a person, with the same amount, if not type, of insecurities as you have.
Also, if you feel you're being annoying to others, find out what it is that may be annoying those people. Ask them if you're being annoying and what it is they find annoying. If they won't give you a straight answer or they say, "No.", then you're either not annoying to them or they need to sort out their problem with you on their own.....Either that or their problem with you isn't a big enough issue that they feel you need to change because they have that problem with you.
I used to be a withdrawn person, but where I am in my life right now, I'm tending to be more outspoken and direct with people. If someone's blatantly in my space or annoying me, I tell them straight up. If they're not listening to me, I'll yell. If they're being annoying, I tell them to cut it out.
I suppose that part of my "coming out of my shell" has been due to me starting to drink about 8 months ago. Since alcohol, at least for me, removes many of my inhibitions, I've said things that I wouldn't have said otherwise, and those experiences (What I've remembered, anyway

) have been used as a base for my current reactions and actions in my everyday life.
I'm not telling you to start drinking or go to parties. Do what you want to do. My point is that a person can change, at least over time. It may take a while, but if you want to change who you are and how you act, you only have to make it happen.
P.S. Zoloft has caused problems for my mother as well (She had depression for many years, although [I believe, as does she] she's got rid of it now). Consume carefully, and also remember that sometimes the medicine is more an illness than your illness.