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Silenus I can imagine getting tired of Touchwiz, I think Sense is a little better looking, but even without rooting you can pretty much personalize Android phones like you want them, IMO. Sometimes a switch of brand can be nice. The Samsung devices are all pretty similar afterall (and very bloated with apps by default), and some of their stuff has a bit of a cheap/plasic feel to them (although I really like Samsung a lot better in general than I like Apple despite that).
As for the M8, I read it's a good phone except for the camera (a traditional weak point of HTC). I take it HTC didn't repeat all of the mistakes that the OneX had in their later models. If it can actually have more than 2 apps open at once without force closing them (which is what the OneX does) it shouldn't be bad.
I personally prefer the S5's screen over the one in the M8, but that's not to say the M8 has a bad display in itself. One thing HTC's always done well is the build quality of their phones, they're very sturdy.
Maybe for you it's the same as me but reverse, I was a long-time HTC user who got dissapointed.
My first HTC was a Diamond, which had a very premium look and feel right down to the packaging (Diamond-shaped case). I still have it but a Windows Mobile device is pretty useless in this day and age.
I had a Desire HD after that, which I absolutely loved as well (not as pretty as the Diamond was, but just an excellent device). If it didn't die (due to my own error) I might very well still use it now.
After that, the OneX was a terrible dissapointment and a frustrating to use device. That's why I switched over to Samsung (Galaxy S5) this year. After keeping up with the OneX for nearly 2 years, it's a delight to use. The M8 can't possibly be as bad as the One X, but that experience was bad enough to ditch HTC... so, I'm happy to have switched.