Zipped N64 games versus UN-zipped N64 games.

My OS = Windows 7 home premium 64-bit.
My laptop = Gateway NV50A.
My CPU = AMD phenom II X2 N660 dual-core processor.
My graphics card (either that or it's my graphics chip set = ATI mobility radeon HD 4250.
My RAM = 4 GB DDR3.
My hard drive = 500 GB, WDC WD5000BPVT-22HXZT1 ATA device.
My CD/DVD reader & writer = Optiarc DVD RW AD-7585H ATA device.
My monitor = Generic PnP monitor.
My sound devices = ATI high definition audio device, Realtek high definition audio.
My usb game controller = Logitech rumblepad 2 G-UF13.
I didn't build this laptop. I bought it online.
Ask me for any more info.

I heard that if an N64 game is inside a zip file, that the game will play slower than if it wasn't inside a zip file. True or not? & if it is true, then will my system (see above) feel it?