Depends on the game, so no.Desmume runs better than No$Gba for me and doesn't require addons just to use texture filters , plus as far as i know it doesn't have any issues with saving.
but i was noticing some "lag" sometimes.if you had checked the faq you would see that the 40% means nothing significant to you and all that matters is the 60fps which is a perfect score.
i know what faq (frequently asked questions) means.software has a homepage. the homepage has documentation. one of these documentations is the "faq" where every question anyone thinks to ask is already answered.