you may need to delete the epsxe registry..... then run epsxe again to make a new one...
click on the start menu, run, type in "regedit"
HKEY_CURRENT_USER\Software\epsxe\config
check that key for the control settings....
click on the start menu, run, type in "regedit"
HKEY_CURRENT_USER\Software\epsxe\config
check that key for the control settings....