From the details you provided, I'd suggest using Pete's D3D (though someone with a TNT of their own is welcome to correct me), Internal SPU and either the native ePSXe or Pete's CD plugin.
For your video configuration I'd start at a low resolution/color depth and add enhancement until your frame rate begins to suffer. There's very little configuration for the other plugins, actually, be sure to set your CD preferences to the drive in which you've inserted your PSX CD and, if you make use of Pete's CD, give speed limiting a try @ 2x.
For your video configuration I'd start at a low resolution/color depth and add enhancement until your frame rate begins to suffer. There's very little configuration for the other plugins, actually, be sure to set your CD preferences to the drive in which you've inserted your PSX CD and, if you make use of Pete's CD, give speed limiting a try @ 2x.