Experiment, experiment, experiment.... each person on this board has his/her own favourite plugin settings. Find the one that works best for you. Heck, even each game has its own 'best' plugin settings.
Looking at your specs, I'll try the following for the 'base' configuration:
Video: Pete's OpenGL (since you got a GeForce3)
CDROM: ePSXe internal (Pete's also works pretty well)
Sound: ePSXe internal (not the best, but it works)
Experiment with the Sound plugin.... there's Iori's, Null's, and many others.... search this board for other recommendations. There have been quite a number of topic on this already.
Looking at your specs, I'll try the following for the 'base' configuration:
Video: Pete's OpenGL (since you got a GeForce3)
CDROM: ePSXe internal (Pete's also works pretty well)
Sound: ePSXe internal (not the best, but it works)
Experiment with the Sound plugin.... there's Iori's, Null's, and many others.... search this board for other recommendations. There have been quite a number of topic on this already.