Use the Escape Key to pause emulation, and these options should come back within a few seconds. The game will automatically continue after you use the change disc function or you can use Run-> continue to continue without changing discs. I assume you are running in a windowed mode?
Also, most multi-disc games have a fail-safe built in when swapping discs. They allow you to save the game before you swap, so you can "turn off" the console and load the save file on the next disc to continue normally. This should also work in ePSXe by quitting the emulator and then running the game from disc 2 etc... and loading the save you made before the swap.
Also, most multi-disc games have a fail-safe built in when swapping discs. They allow you to save the game before you swap, so you can "turn off" the console and load the save file on the next disc to continue normally. This should also work in ePSXe by quitting the emulator and then running the game from disc 2 etc... and loading the save you made before the swap.