(0) please inform: sound card sample rate + bit depthYes
With Windows 10 problem
With Windows 7 no problem
0.a right-click the speaker icon in your notification area then choose playback devices;
0.b select your speaker, then, click properties;
0.c choose the advanced tab;
just inform the options in use, no need to change the settings.
(1) check power plan and power managment clock
try High performance
HowToGeek - Should You Use the Balanced, Power Saver, or High Performance Power Plan on Windows?
(2) disable video drivers vsync options + triple buffering + application profiles
try disable VSync and Triple Buffering (both: globally and per program settings).
Intel - Enabling and Disabling Vertical Synchronization
AMD - Wait for Vertical Refresh (tip for others users)
NVIDIA - Adaptive VSync
(3) disable Game DVR and Game BAR
(4) disable Game Mode
(5) install MS libs
5.a restart your machine
Windows 10 natively operates through a mode called "Fast Startup", although it decreases boot time, some problems are persistent without proper restarting of Windows. the "Restart" option makes the machine ignore fast startup even if it is enabled and is therefore recommended here.
more info - just restart, you don't need to change any settings
5.b install some libs
both libraries are originals from Microsoft and installing both is a safe process without prejudice.
to install VCpp, run the included install_all.bat with admin privileges (right click, "Run as administrator");
to install DirectX, run the executable as administrator (right click, "Run as administrator");
Visual C++ Redistributable Runtimes All-in-One (Jun 2019)
DirectX End-User Runtimes (June 2010) [DirectX9]
5.c restart your machine
your feedback is very important!
if the problem persists with both plugins (ePSXe GPU Core and Pete's OpenGL2 Core) after all changes, consider using RetroArch Beelte PSX. I believe that following the Safe Guide you will have little or no difficulty!
RetroArch - Safe Guide