Well,I use Pete's OGL plugin,
the internal SPU with all options checked,
the internal cddrom plugin with "enable accurate crdom timing"checked.
I use the dtlh3002 Bios.
SIO irq is always enabled.
And I set to autodetect for the country.
The Resident Evil series all work with the same configuration on my - HP Pavilion - Celeron 600 mhz , Voodoo 3 3000 - with 64 megs of ram...there plugins are as followed- GPU ( Pete's D3D 1.50 ) it's settings required from experience are Special game fixes - short DMA.....Framebuffer textures - gfx card. The SPU ( Pete's DSound 1.10 ) all checked , enable SPU IRQ hack . CDrom plugin ( ePSXe core 1.40 ) enable accurate cd timing . Bios 7502.-----NOTE----- These are what I came up with after about 6 hours of testing , but Perfection is the key. I found these settings a must for me to run them , I hope this helps anyone.