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15,294 Posts
sounds like DEP is behind your problem. just disable it altogether or do like it says and add epsxe to the exceptions list and you should be fine.
http://en.wikipedia.org/wiki/Data_Execution_Prevention
http://www.zensoftware.co.uk/kb/article.aspx?id=10002
http://en.wikipedia.org/wiki/Data_Execution_Prevention
http://www.zensoftware.co.uk/kb/article.aspx?id=10002