Pete's Software is technically the best plugin, it is the most compatible, and it supports graphic features that are very complicated and/or difficult to pull off in hardware.
(though most people use pete's OpenGL/D3d or Lewpys Glide because hardware is faster and looks better)
The ePSXe's internal sound driver is reguarded by many as being the best overall SPU.
Pete's CDR 1.16 I would reguard ad being the best CDrom plugin, because it can automatically apply patches to games, and has error retrys for scratched CD's.
(though most people use pete's OpenGL/D3d or Lewpys Glide because hardware is faster and looks better)
The ePSXe's internal sound driver is reguarded by many as being the best overall SPU.
Pete's CDR 1.16 I would reguard ad being the best CDrom plugin, because it can automatically apply patches to games, and has error retrys for scratched CD's.