You have the typical SPU2 bug.
With the null pluging It will go fine, without sound
But if you use PEOPS plugin maybe the game will work ok with sound (or you will only get stranges sounds), but if the plugin doesn't work the emu will crash.
It is the same thing that happens in Disgaea, and other games.
Your only option is to play without sound until there is a new version of the plugin (or the emu).