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LuismaSp89 Well, I'm guessing that the latest 2.0 versions of ePSXe use the same "core" plugin of Pete'sOGL 2.9 for its OpenGL 2.0.0, so some settings, like shader directory, might be in conflict with the specific "GPU" plugin settings in the registry. When I used shaders extensively, I gave up trying to make settings for specific games, so I simply entered my shaders folder and copied the folder path of the shader I wanted, and pasted on the Pete'sOGL2 shader GUI whenever I needed to.
By the way, the current ePSXe still has some GUI issues, that I can't remember specifically right now since it's been a long time since I used it, but crazy things used to happen... not saving options correctly is one of them. One main issue that I still have, is that checking or unchecking "Screen filtering: a nice fullscreen filter" option won't take effect until I restart the emulator, ePSXe or PCSXR-PGXP. That might be specific to the plugin though.
Again, registry settings suck for something that is not even properly "installed" (by option).
#.ini4PSXConfig #EmulationMatters
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Don't take that too seriously

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