Thanks for the reply. Unfortunately, I'm still having a problem with memory card formatting. When I start up ePSXe, and get to the main menu of whatever game I'm using, I press F4. To be sure that pressing F4 has an effect on the ePSXe program, I hit my Windows button, and sure enough the DOS window now says "SIO irq enabled.". Great, so now all I have to do is the normal PSX functions involved with formatting/saving. So I format the memory card file, save my settings, play my game, save it, and hit F4 again. I hit the Windows key again to check my DOS window to confirm that the F4 stroke has registered, and it has ("SIO irq disabled.").
Now I exit to Windows, exit from ePSXe, and start ePSXe back up again. When I get to the main menu of the game, I hit F4. Then I proceed to the memory card to load my options, and the game tells me that the memory card is not formatted !?!? If this rings a bell I would certainly appreciate any input or advice. Thanks again.