I have played ePXSefine before without it ccrashing, but lately, whenever i try to load a save state, i get a windows pop up that says ePXSe needs to close... I havelooked at the log and it says "SPU plugin does notsupport save state" Any suggestions?
What SPU plugin are you using? I've used savestates with both Eternal and P.E.Op.S. and saving a savestate with one plugin and loading it up with a different plugin enabled and I haven't had any problems.
This is a longshot but go and download the "NULL driver" plugin and try if you can load ur savestate using it. If you can, make a new savestate or better, save to memcard. Then switch to eternal or peops.