Indeed... DOA is needs Mooby2 to stream the audio. We just tested and verified. Unfortunately you cannot stream CDDA off the disc. There a re a few other games like this as well (Battle Arena Toshinden and Twisted Metal for example).
What we did:
1. Created a BIN / CUE file from our original disc.
2. Configured Mooby2 to play CDDA tracks once then stop and increased CDDA volume
3. Used Eternal SPU plugin or PEOPS SPU