It looks like your problem is CDROM reader related, I agree with Matias.
If enabling accurate cdrom timing doesn't work I strongly suggest to select another cdrom plugin .
I uses Epsxe CDR ASPI core 1.4.0 plugin and it works fine for me ( including for GT1 and 2 ).Of course, some cdrom plugins works better with some cdrom brands, so try them all.
And don't forget Epsxe motto: Tweak, tweak and ... tweak
I hope this helps