- Scanlines: off
- Mdec filter: on
- Screen filtering: on
- Shader effects: 0/1
- Flicker-fix border size: 0
- GF4/XP crash fix: off
- Game fixes: off 
These are the settings I use. You will need to set your Desktop Resolution to something else like 800x600 or 1024x768. Also, I don't think your card will be able to handle an internal X/Y resolution of '2', so set them to '1' or '0'. For VRAM, set to whatever amount of video RAM you graphics card has. (or just set to '0' [Auto]).
PS - These settings are my ideal settings for FF7, so other games may not work well, if at all with these settings. Usually, you will just need to adjust one or two settings and/or enable a special game fix. Buffer size in the Eternal SPU plugin dialog may need to be tweaked to somewhere between 20 - 48 depending on your system.
PSS - You may also need to turn off Screen Filtering as that filter is very shader/fillrate heavy.
i recommend switching to the OGL1, or D3d plugins as i mentioned earlier, you will not really be missing out on anything that you already are anyway due to the limits of your hardware and what the OGL2 requires for the use of the higher-end features it is capable of.