when you said you added it to DEP did you mean you added it to the exceptions list of programs to exclude or the list of programs that DEP remains active on?
just making sure. alright how are you loading the images, are you mounting them on a virtual drive or are you doing the file>runISO to load them directly from their location on your HD?
where is epsxe stored on your HD and what are you launching from, the executable or a shortcut to it? you should also be able to right click the shortcut and select run as administrator, if it doesnt let you then enable administator privileges.
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