I have a Yamaha 724f PCI sound card and it works ok for ePSXe (internal SPU and Null2).
I think as long as your sound card has directx support, you can use them with ePSXe. You might want to try to download the latest drivers for your sound card and reinstall directx 8.
I think as long as your sound card has directx support, you can use them with ePSXe. You might want to try to download the latest drivers for your sound card and reinstall directx 8.